Ok! A
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@AcademicChatter #ScienceTwitter
1) The research question is important. Esp if you want to go into academia, choose a big picture ques! Like my labmateâs âWhat effect does neural activity have on the BBB?â
@AcademicChatter #ScienceTwitter
1) The research question is important. Esp if you want to go into academia, choose a big picture ques! Like my labmateâs âWhat effect does neural activity have on the BBB?â
(see his paper below on my timeline!!). Rather than âwhat does X gene do in X disease.â If youâre thinking big picture, youâll plan experiments in a way that might yield more unexpected, exciting discoveries. And youâll have greater mental flexibility to follow new findings!
2) Do an experiment until youâre sure that you have a negative or a positive result. This means testing an assay with pos/neg controls before you start manipulating, so that you know itâs a viable assay & youâre sufficiently good at it. I wasted SO much time starting experiments
and then abandoning them when I didnât see the strong positive result I wanted. Youâll save time and money in the long run if you do things more thoroughly and conclusively! And practice(!!) before you do real the experiment.
3) Donât be married to your hypotheses!!! Always have
3) Donât be married to your hypotheses!!! Always have
alternate hypotheses in mind, and try to do experiments that test them as you are testing your primary hypothesis. If your primary hypothesis is correct, negating the alternates will make it stronger anyway!
4) Donât shy away from experiments/analyses that seem complicated.
4) Donât shy away from experiments/analyses that seem complicated.
You can learn anything with time and training! And reading & YouTube
https://abs.twimg.com/emoji/v2/... draggable="false" alt="đ" title="Gesicht mit FreudentrĂ€nen" aria-label="Emoji: Gesicht mit FreudentrĂ€nen">. & if it makes more sense, pull in a collaborator to help! You donât have to learn everything yourself. Bc the first author gets most of the credit, we have a perception that they did all the work. Not true!
5) Ask for help when you need it. And if you havenât joined a lab yet, join the rotation lab where you feel the most comfortable asking for help. Cannot overstate the importance of helpful colleagues. So grateful to have amazing ones
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6) If you think you might want to go into
6) If you think you might want to go into
academia, practice grant-writing! Sometimes you have to seek this out. Ask your PI to read their grants. Ask if you can try writing them yourself and get feedback. Itâs an essential skill and one not usually taught well in programs.
7) Build a network! I have loved sci Twitter
7) Build a network! I have loved sci Twitter
for this. Another suggestion is to go to conferences your PI is also going to, so that they can introduce you to other PIs they know. Shoutout to the amazing Barres lab fam whom I have gotten to know this way
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8) Reading, thinking, and planning count as work!! You donât have
8) Reading, thinking, and planning count as work!! You donât have
to be doing experiments in the lab to be productive. And you will be WAY more efficient if your experiments are better planned. I still have trouble tearing myself away from physical experiments. Do as I say, not as I do
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9) Related to the last one - make sure your brain
9) Related to the last one - make sure your brain
has time to relax. My best experiment ideas have come while running
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10) Donât compare yourself to others. Easier said than done. But if two people have different strengths, they might look at each other and see that the other has strengths they lack. Insecurity can turn
10) Donât compare yourself to others. Easier said than done. But if two people have different strengths, they might look at each other and see that the other has strengths they lack. Insecurity can turn
into ugly behavior. Itâs better to be open about your insecurities and imposter syndrome rather than try to âprove yourselfâ to others. If they are also insecure, this âproving oneselfâ can appear mean! Better to bond over both of your insecurities and compliment each other
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11) You
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https://abs.twimg.com/emoji/v2/... draggable="false" alt="đ" title="Applaus-Zeichen" aria-label="Emoji: Applaus-Zeichen"> Not
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https://abs.twimg.com/emoji/v2/... draggable="false" alt="đ" title="Applaus-Zeichen" aria-label="Emoji: Applaus-Zeichen"> Experiments. Experiments will fail. Donât take it personally. Find something to add to your life thatâs always rewarding, like science outreach.
12) Be respectful, KIND, helpful. Scientists are human beings & weâre all learning from each other
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12) Be respectful, KIND, helpful. Scientists are human beings & weâre all learning from each other