Sulfoglycolysis is a pathway through which the novel sulfosugar sulfoquinovose is metabolised. In this pre-print we report crystal structures of core enzymes in sulfoglycolysis, defining how they recognize the sulfonate headgroup. @ProfG101 @ethangbaus
https://chemrxiv.org/articles/preprint/The_Molecular_Basis_of_Sulfosugar_Selectivity_in_Sulfoglycolysis/12974237/1">https://chemrxiv.org/articles/...

We studied the sulfoglycolytic Embden-Meyerhof-Parnas pathway, reported by Cook/Schleheck. Although superficially like classical glycolysis, it is encoded in a separate operon. We show that sulfoglycolytic enzymes do not act on glycolytic intermediates https://www.nature.com/articles/nature12947">https://www.nature.com/articles/...

This work is significant because sulfoquinovose is a major reservoir of sulfur in the biological world – an estimated 10 billion tonnes are made annually.
https://en.wikipedia.org/wiki/Sulfoglycolysis">https://en.wikipedia.org/wiki/Sulf...

For a contemporary tale of the importance of sulfoquinovose in the gut, see this thread from @LoyTeam https://twitter.com/LoyTeam/status/1300430266650034177?s=20">https://twitter.com/LoyTeam/s...