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@McGillGenome @INSPQ have thus far sequenced genomes of 734 Québec residents infected w/ #COVID19 to unravel the genomic epidemiology of the infection (sources of introduction) in QuébecVideo of automated sequencing:
Below is summary of findings
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Samples were collected between mid-Feb to April 1, 2020
Sequence analysis + travel history showed:
32.7% of infections came from Europe, with France contributing 12.1% of infections
31% from Caribbean/Latin America
23.9% from U.S.
1.2% from Asian, none from China
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Sequence analysis + travel history showed:
32.7% of infections came from Europe, with France contributing 12.1% of infections 31% from Caribbean/Latin America 23.9% from U.S. 1.2% from Asian, none from China2/5
Based on the phylogeny of the earliest reported cases, it is possible the first case reached Québec City from the United Kingdom as early as end of January!
This confirms that #COVID19 had spread outside China a lot earlier than originally announced.
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This confirms that #COVID19 had spread outside China a lot earlier than originally announced.
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According to the results, the virus entered Québec during the spring break & could have been carried into the province by as few as 247 people.
You can view the pre-print here: https://virological.org/t/genomic-epidemiology-of-early-introductions-of-sars-cov-2-into-the-canadian-province-of-quebec/553
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You can view the pre-print here: https://virological.org/t/genomic-epidemiology-of-early-introductions-of-sars-cov-2-into-the-canadian-province-of-quebec/553
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Lastly, this great work is possible through support from @GenomeCanada's CanCOGEn project, @InnovationCA,
@CalculQ, @ComputeCanada
This work and analysis is ongoing.
End of thread.
@CalculQ, @ComputeCanada
This work and analysis is ongoing.
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