2/x Some context: In the US, there are still some local testing shortages. But bc capitalism, private companies like @LabCorp, @everly_well, and @LetsGetChecked have started offering @US_FDA emergency-use authorized at home collection kits that get shipped off to a lab.
3/x These kits are ~$120 out of pocket, but insurance can cover them. It& #39;s a swab + PCR test, looking for SARS-CoV-2 genetic material. They typically return results in a couple of days, and you don& #39;t have to leave your home.
4/x The problem is, even at their best these tests have a pretty high false negative rate. Bc of #COVID19& #39;s long incubation period—median 4-5 days, sometimes 14—if you take a test too early after being exposed, it may not have had enough time to replicate in your body.
5/x This review from @JohnsHopkins looked at the false negative rate of #COVID19 tests and found that the first day of exposure, false negative is 100%; day 4 (probs no symptoms), it& #39;s 67%. Day 8, a bit after most people show symptoms, it& #39;s 20%. https://www.acpjournals.org/doi/10.7326/M20-1495">https://www.acpjournals.org/doi/10.73...
6/x In normal times, false negatives don& #39;t affect how medicine is practiced; if someone has flu-like symptoms but tests negative for the flu, you& #39;d assume the test was wrong. If you& #39;re a doc, you treat accordingly. If you& #39;re a friend, you stay away until they& #39;re better.
7/x In #COVID19 times, we& #39;re using testing to try to identify asymptomatic/pre-symptomatic carriers, who we know exist. That& #39;s a new use for testing; usually it shows public health officials where outbreaks are happening.
8/x If you& #39;ve known that you& #39;ve been exposed to someone who has #COVID19 and get a negative test result, you should assume it& #39;s wrong, @Michael_Hochman from @KECKSchool_USC told me. You should isolate for 14 days, and assume that you& #39;re an asymptomatic carrier.
9/x That said, isolation is REALLY BAD for mental health. We need to see loved ones—so if you do, go ahead and take a test. But be mindful of your exposure levels before/after, the risks of those in the group, the activities you do—stay outside when you can, wear masks if you can
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