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The therapeutic action of our candidate drug 2OHOA is based on #Melitherapy 
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🔬" title="Mikroskop" aria-label="Emoji: Mikroskop"> This exploits the interactions between lipids and proteins that happen in the cell membrane. Want to know more? Follow the thread! https://abs.twimg.com/emoji/v2/... draggable="false" alt="🧵" title="Thread" aria-label="Emoji: Thread">
This exploits the interactions between lipids and proteins that happen in the cell membrane. Want to know more? Follow the thread! https://abs.twimg.com/emoji/v2/... draggable="false" alt="🧵" title="Thread" aria-label="Emoji: Thread">" title="The therapeutic action of our candidate drug 2OHOA is based on #Melitherapy https://abs.twimg.com/emoji/v2/... draggable="false" alt="🔬" title="Mikroskop" aria-label="Emoji: Mikroskop"> This exploits the interactions between lipids and proteins that happen in the cell membrane. Want to know more? Follow the thread! https://abs.twimg.com/emoji/v2/... draggable="false" alt="🧵" title="Thread" aria-label="Emoji: Thread">" class="img-responsive" style="max-width:100%;"/>
There is something that all the cells in our body have in common: they all have a membrane that separates them from the outside https://abs.twimg.com/emoji/v2/... draggable="false" alt="🚧" title="Baustellenschild" aria-label="Emoji: Baustellenschild"> This is made of a double layer of lipids that have proteins embedded in it.
These proteins play many important roles: they allow the cell to let molecules in and out https://abs.twimg.com/emoji/v2/... draggable="false" alt="🔃" title="Auf-und Abwärtspfeile in offenem Kreis im Uhrzeigersinn" aria-label="Emoji: Auf-und Abwärtspfeile in offenem Kreis im Uhrzeigersinn"> and also to communicate with other cells and the outside https://abs.twimg.com/emoji/v2/... draggable="false" alt="🗨" title="Linke Sprechblase" aria-label="Emoji: Linke Sprechblase">
Some of these proteins act as receptors for chemical signals that produce relevant changes in the cell https://abs.twimg.com/emoji/v2/... draggable="false" alt="📣" title="Anfeuerungsmegafon" aria-label="Emoji: Anfeuerungsmegafon"> For example, they can receive a signal that makes the cell to divide, to change the expression of their genes or even to die https://abs.twimg.com/emoji/v2/... draggable="false" alt="☠" title="Totenkopf" aria-label="Emoji: Totenkopf">
Sometimes these changes are behind the onset of some diseases https://abs.twimg.com/emoji/v2/... draggable="false" alt="🩺" title="Stethoskop" aria-label="Emoji: Stethoskop"> An example of this is #cancer: if the signals that make the cells divide get unbalanced, they start to do so out of control, producing a tumour.
Here is where #Melitherapy can make the difference! This therapy targets the lipids that form the membrane.
Proteins need a certain interaction with membrane lipids to stay in it. It the lipids change, proteins may lose their hook and enter the membrane. Thus, they would stop receiving any signal https://abs.twimg.com/emoji/v2/... draggable="false" alt="🗨" title="Linke Sprechblase" aria-label="Emoji: Linke Sprechblase">https://abs.twimg.com/emoji/v2/... draggable="false" alt="❌" title="Kreuzzeichen" aria-label="Emoji: Kreuzzeichen">
To sum up, if we manage to change at will the composition of the cellular membrane, we can control the signals that the cell receives and stop those that are producing the disease https://abs.twimg.com/emoji/v2/... draggable="false" alt="👩⚕️" title="Woman health worker" aria-label="Emoji: Woman health worker">
And this may be useful for #glioblastoma, as some signalling pathways related to cell proliferation happen through the cell membrane!
If you want to know how we take advantage of this novel approach, visit our webpage! https://abs.twimg.com/emoji/v2/... draggable="false" alt="👇" title="Rückhand Zeigefinger nach unten" aria-label="Emoji: Rückhand Zeigefinger nach unten"> http://clinglio.eu"> http://clinglio.eu
