Academic report from Greece on hydroxychloroquine posology against COVID-19.
The country, which has the oldest population in Europe, has used HCQ against the pandemic from Day 1.
https://www.tandfonline.com/doi/full/10.1080/00498254.2020.1824301
"the dosing scheme proposed for a 70kg adult with moderate COVID-19 symptoms would be 600mg upon diagnosis, 400mg after 12h, 300mg after 24h, 200mg after 36h, followed by 200mg BID for 4 days and 200mg OD for 5 days"
Here is the comparison with the outlandish RECOVERY dosing:
The official French drug compendium (Vidal) puts the HCQ overdosing limit at 25 mg/kg (2g for an man of 80kg).
Remember that RECOVERY patients were gravely ill (77% in respiratory distress) when treated with very high doses.
A RCT-proof confounding factor that cannot be fixed.
It cannot be proven that the unexpectedly and abnormally high cumulated dosing of HCQ is not the causal factor behind the excess mortality drift in grave patients visible in the RECOVERY study.
Which means that RECOVERY is clinically inconclusive due to poor design, RCT or not.
And an old tweet for background info: https://twitter.com/Covid19Crusher/status/1269635739370885120?s=20
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