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Up next at #ESCCongress is the BRACE-CORONA trial from Brazil on continuing or stopping ACE/ARBs in COVID-19
https://clinicaltrials.gov/ct2/show/NCT04364893
1/">https://clinicaltrials.gov/ct2/show/...
https://clinicaltrials.gov/ct2/show/NCT04364893
1/">https://clinicaltrials.gov/ct2/show/...
why does it matter?
see the #NephJC background on the topic here - with the science and the evidence so far
http://www.nephjc.com/news/covidace2
https://www.nephjc.com/news/covi... href="https://twtext.com//hashtag/ESCCongress"> #ESCCongress
2/
see the #NephJC background on the topic here - with the science and the evidence so far
http://www.nephjc.com/news/covidace2
2/
this is just the first of many trials ongoing to report
see summary here http://www.nephjc.com/news/covidace2 ">https://www.nephjc.com/news/covi... collated by @Ricky_Turgeon & @jordy_bc
#ESCCongress
see summary here http://www.nephjc.com/news/covidace2 ">https://www.nephjc.com/news/covi... collated by @Ricky_Turgeon & @jordy_bc
#ESCCongress
He calls it rennin 
https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤦🏽♂️" title="Mann schlägt sich die Hand vors Gesicht (mittlerer Hautton)" aria-label="Emoji: Mann schlägt sich die Hand vors Gesicht (mittlerer Hautton)">
Is that a cardiologist out there?
#ESCCongress
Is that a cardiologist out there?
#ESCCongress
trial design
excluded Entresto-users
also those on 3 or more antiHT drugs. Hmm
Good primary outcome
#ESCCongress
excluded Entresto-users
also those on 3 or more antiHT drugs. Hmm
Good primary outcome
#ESCCongress
since we - the #NephJC #Covidace2 workgroup lead by @Nephro_Sparks had gone on out a limb sorta to advice this back in March https://www.nephjc.com/news/covi... #ESCCongress" title="https://abs.twimg.com/emoji/v2/... draggable="false" alt="😅" title="Lächelndes Gesicht mit offenem Mund und Angstschweiß" aria-label="Emoji: Lächelndes Gesicht mit offenem Mund und Angstschweiß"> since we - the #NephJC #Covidace2 workgroup lead by @Nephro_Sparks had gone on out a limb sorta to advice this back in March https://www.nephjc.com/news/covi... #ESCCongress" class="img-responsive" style="max-width:100%;"/>
Most societies also did of course, see table collated by @Jordy_bc
Great to see that sensible thinking in the scientific way turns out to be correct unlike the speculation (in BMJ, Lancet, JH)
#ESCCongress
Great to see that sensible thinking in the scientific way turns out to be correct unlike the speculation (in BMJ, Lancet, JH)
#ESCCongress
Should these ongoing trials go on?
These trial interventions are simila to #BRACECORONA. But we don’t see any signal of harm so far. I would argue we need replication and ext validation, so they should go on #ESCCongress
These trial interventions are simila to #BRACECORONA. But we don’t see any signal of harm so far. I would argue we need replication and ext validation, so they should go on #ESCCongress
And these trials are different: starting an ARB! They should happen of course - though would nicer to have one or two large RCT than many small ones of course
#ESCCongress
#ESCCongress
Plus these which will be starting soon or perhaps have already started by now
These trial tables collated by @Ricky_Turgeon & @jordy_bc
All this and more at the #NephJC #COVIDACE2 page http://www.nephjc.com/news/covidace2
https://www.nephjc.com/news/covi... href="https://twtext.com//hashtag/ESCCongress"> #ESCCongress
These trial tables collated by @Ricky_Turgeon & @jordy_bc
All this and more at the #NephJC #COVIDACE2 page http://www.nephjc.com/news/covidace2
#ESCCongress" title="Plus these which will be starting soon or perhaps have already started by now These trial tables collated by @Ricky_Turgeon & @jordy_bc All this and more at the #NephJC #COVIDACE2 page https://www.nephjc.com/news/covi... href="https://twtext.com//hashtag/ESCCongress"> #ESCCongress" class="img-responsive" style="max-width:100%;"/>
