Thread 1/5: I suspect the reasons behind the POTUS Emergency Use Authorization (EUA) for plasma Rx may have an ulterior motive: They are working to lower the bar for EUAs in general, in order to push what they really want - an EUA for a COVID19 #vaccine
Thread 2/5: Regarding plasma Rx, the studies I& #39;ve seen from @MayoClinic @HopkinsMedicine show some benefit, esp when given early in the course of the illness and in large amounts. I remain enthusiastic about continuing this approach - at least until new mabs become available
Thread 3/5: Whether or not plasma Rx is released through an EUA or the existing expanded access EAP from my standpoint doesn& #39;t make much difference, but the docs on the frontline tell me an EUA makes it easier, with less paperwork, tracking. But that& #39;s not the point....
Thread 4/5: I think the reason why the White House got involved has less to do with an EUA for plasma Rx (although maybe it& #39;s a way they can appear to be doing something substantive) and more to do with getting the public feeling comfortable with EUAs in general.
Thread 5/5: Possibly they think this could provide a "glide path" for a future EUA for a COVID19 #vaccines, potentially a pre-election vaccine EUA. I hope I& #39;m wrong but I& #39;m being vigilant...
Thread 6/5: (extra one sorry) so maybe nothing wrong per se about an EUA for plasma Rx. And maybe OK for @US_FDA to agree to this. But the White House may have their eyes on a bigger target.
Thread 7/5: (OK 2 extra) just for the record (to be unambiguous), if I had #COVID19 and was sick, I would request convalescent plasma, special congrats to @DrMJoyner @ShohamTxID @ACasadevall1 for their important work on this...my hope is that the new mabs become available soon
Thread 8/5 (OK 3 extra) it& #39;s just so awful the way the White House confuses the real science with the fake science for their hidden agendas. But that& #39;s the lesson: This is how anti-science movements work, they string real facts factoids with falsehoods to create false narratives
You can follow @PeterHotez.
Tip: mention @twtextapp on a Twitter thread with the keyword “unroll” to get a link to it.

Latest Threads Unrolled: