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Daily reminder:
— Coronavirus main host is a bat
— Bats are not found in Wuhan/Hubei region
— Bats would have been hibernating around time of the outbreak
— COVID19 is extremely susceptible to both heat and UV light
— Bioinformatics data storing genetic
sequence of a
— Coronavirus main host is a bat
— Bats are not found in Wuhan/Hubei region
— Bats would have been hibernating around time of the outbreak
— COVID19 is extremely susceptible to both heat and UV light
— Bioinformatics data storing genetic
sequence of a
coronavirus back in 2013, had its name changed by the Chinese — a deliberate attempt to coverup the fact that the virus shares a large percentage of the sequence of COVID19
of COVID19
— COVID19 can only spread indoors. This is not to say it cannot eventually evolve to spread outdoors but nonetheless evolved to spread indoors. This is highly conspicuous and indicative of laboratory origin
— Genetic sequence of COVID19 indicates that the virus is a chimera
— Genetic sequence of COVID19 indicates that the virus is a chimera
Meaning its genetic sequence is made up of more than one type of virus. This is evident when analyzing the spike protein. The spike protein is an integral protein that allows the virus to attach to the ACE2 receptor in humans.
S Protein = Spike Protein
S Protein = Spike Protein
When analyzing the sequence of the spike protein of COVID19 it becomes apparent the virus is a chimera of two viruses:
— Spike protein of ancestral bat strain RaTG13
— However the receptor binding motif (RBM) in its spike protein is replaced by the RBM from a pangolin strain
— Spike protein of ancestral bat strain RaTG13
— However the receptor binding motif (RBM) in its spike protein is replaced by the RBM from a pangolin strain
In addition to the swap of RBM:
— 4 amino acids are inserted. This creates a furin cleavage site.
What does all of this do? As previously explained by virologists—significantly expands the “repertoire” of the virus and allows it to infect more types of cells
— 4 amino acids are inserted. This creates a furin cleavage site.
What does all of this do? As previously explained by virologists—significantly expands the “repertoire” of the virus and allows it to infect more types of cells
Why is this important?
— The furin site allowed the virus to “jump” from bats to humans
— This ability to jump from bats to humans along with the near impossibility of the genetic change occurring in humans indicates lab manipulation
— For the virus to occur naturally it would
— The furin site allowed the virus to “jump” from bats to humans
— This ability to jump from bats to humans along with the near impossibility of the genetic change occurring in humans indicates lab manipulation
— For the virus to occur naturally it would
need to have an intermediate animal host, where it evolved and then gained the capability to infect humans. There is no indication or evidence of an intermediate animal host.
This came from a lab. This came from the Wuhan lab.
This came from a lab. This came from the Wuhan lab.
The Wuhan lab had been working on chimera viruses since 2007. There is no doubt or question on whether or not they had the capability of doing this. They have been doing this for 13 years. The question is, why cover it up and who else was associated with the lab?!
The head of coronavirus research at the Wuhan Institute of Virology, Shi Zhengli, has done plenty of work replacing RBM in one virus and substituting it with the RBM from another virus. Some of the work also includes adding a furin site to these chimera viruses.
From 2007-2017, a total of at least 8 chimeric coronaviruses were developed at the Wuhan Lab. As recently as 2019, the Wuhan Lab received a 3.7 million dollar grant from the NIH. President Trump put a stop to this and it was not his administration who started this.
A 2019 paper from Shi Zhengli makes some dubious claims justifying this NIH grant: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7097006/
“Currently, no clinical treatments or prevention strategies are available for any human coronavirus. Given the conserved RBDs of SARS-CoV and bat SARSr-CoVs, some anti-SARS-CoV strategies in development, such as anti-RBD antibodies or RBD-based vaccines, should be tested..”
“Future work should be focused on the biological properties of these viruses using virus isolation, reverse genetics and in vitro and in vivo infection assays...”
But what does reverse genetics mean?!?!?!
But what does reverse genetics mean?!?!?!
Look no further than the NIH grant itself:
“In vitro and in vivo characterization of SARSr-CoV spillover risk, coupled with spatial and phylogenetic analyses to identify the regions and viruses of public health concern. We will use S protein sequence data,......”
“In vitro and in vivo characterization of SARSr-CoV spillover risk, coupled with spatial and phylogenetic analyses to identify the regions and viruses of public health concern. We will use S protein sequence data,......”
“....infectious clone technology, in vitro and in vivo infection experiments and analysis of receptor binding to test the hypothesis that % divergence thresholds in S protein sequences predict spillover potential.”
So now that we know a little bit about the basic facts. Let’s examine more about the spike protein. After all, this is how coronaviruses got “crowned.” 
. Corona = crown 
How spike protein is structured in SARS-COV-2 and related viruses
. Corona = crown How spike protein is structured in SARS-COV-2 and related viruses
S protein consists of two subunits: S1 and S2. It is S1 that interacts with the ACE2 receptor, and the place where S1 does so is called Receptor Binding Domain (RBD). The area of the RBD that contacts the ACE2 is known as..... Receptor Binding Motif (RBM)!
Remember the RBM is what is modified in COVID19! 
Let’s look at this another way:
Let’s look at this another way:
Explaination of the figures in the previous tweet:
On January 10th, 2020, the sequence of COVID19 was released. But there was no indication its matched any known virus https://www.ecdc.europa.eu/en/novel-coronavirus/event-background-2019
On January 23rd 2020, Shi Zhengli released a paper suddenly and rather quietly stating that COVID19 was 96% similar to the RaTG13 strain mentioned earlier. https://www.biorxiv.org/content/10.1101/2020.01.22.914952v2.full
In this paper Shi Zhengli mentions that COVID19 is very similar to a strain isolated from Yunnan bats by her team in 2013. This was previously unknown to everyone.....except for members of her own team 
RaTG13 is a special strain, it seems. Check out this genome similarity graph. The higher the curve, the higher the percentage of matching nucleotides. As you can see, in the spike protein (S) gene region (between nucleotides 22k and 25k), only RaTG13 is more or less close to COV2
COV2 = COVID19
