On #diabetes, glucose control, #COVID19, #SARSCoV2
A new @Cell_Metabolism paper on the mechanism for uncontrolled glucose and severe covid19
https://www.cell.com/action/showPdf?pii=S1550-4131%2820%2930365-X
A new @TheLancetEndo review goes deep on why there are worse outcomes https://www.thelancet.com/journals/landia/article/PIIS2213-8587(20)30238-2/fulltext
The one thing I was surprised about in the review was lack of mention of the affinity of #SARSCoV2 to pancreatic islet β cells. This is thought to be another mechanism for new onset #T1D; there have been many cases reported and an ongoing registry
Summary of #SARSCoV2 affinity to ACE2, direct pancreas hit and COVIdiab registry
https://www.nejm.org/doi/full/10.1056/NEJMc2018688
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