1. Doctor Octopus- The Leader, and the only one whose egotistical enough to marshal the rest of the forces together.

Doc can't just *win.* He HAS to stack the deck in his favor, and make others do the hard work for him. https://twitter.com/AnneComics/status/1277911530990899201

2. Electro. Long rang elemental fighter. Electro can hit Spider-Man from a distance, and provide decent cover fire for his allies.

3. Sandman. Close to mid range elemental shapeshifter. Sandman can turn the very environment against Spider-Man, and is difficult to near impossible to defeat in a physical manner.

4. Mysterio. Master of illusion. Not a fighter in any respect, Mysterio can provide debilitating traps and illusions that can disorient Spider-Man's senses.

5. The Vulture. Aerial combatant. The one villain who has the perpetual high ground over Spider-Man. The Vulture can prevent Spider-Man from employing his one tactical advantage over the group, negating Spidey's high flying acrobatics with his own aerial abilities.

6. The Rhino. Pure, brute strength. While not the smartest of fighters, the Rhino provides an overwhelming force that the other members of the Six can't hope to match on their own.