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Oh look. The RECOVERY preprint is out
I am glad I was a staunch advocate we adopt this asap as it was not a typical 'medicine by PR' because the manuscript is sound.
End of story.
Change your practice now. https://twitter.com/greg_folkers/status/1275186349381791744
I am glad I was a staunch advocate we adopt this asap as it was not a typical 'medicine by PR' because the manuscript is sound.
End of story.
Change your practice now. https://twitter.com/greg_folkers/status/1275186349381791744
Here is how i knew this was not a typical medicine by press release
Because, I am a student and critic of 'medicine by press release' https://twitter.com/VPrasadMDMPH/status/1273028969718337536?s=20
Because, I am a student and critic of 'medicine by press release' https://twitter.com/VPrasadMDMPH/status/1273028969718337536?s=20
5 days ago, I doubled down on that thread, and highlighted more reasons why we should adopted this immediately https://twitter.com/VPrasadMDMPH/status/1273319792951214080?s=20
I showed it as a Pascal's wager https://twitter.com/VPrasadMDMPH/status/1273727674670657537?s=20
I blew my top in a podcast https://soundcloud.com/plenarysession/ep257
And now, I have read the paper in its entirety, and I find nothing problematic
And I doubt anyone else will find any red flag.
It will later be published in a journal. NEJM or Lancet is my guess.
If you delayed, you made a bad a call.
Not only in retrospect, but at the time
And I doubt anyone else will find any red flag.
It will later be published in a journal. NEJM or Lancet is my guess.
If you delayed, you made a bad a call.
Not only in retrospect, but at the time
the calculus was clear to adopt
respected investigators
could read protocol
low cost
low potential for rare AE
no FCOI
clear pre-specified subgroups in protocol
large and convincing effect size on
endpoint that matters
respected investigators
could read protocol
low cost
low potential for rare AE
no FCOI
clear pre-specified subgroups in protocol
large and convincing effect size on
endpoint that matters
For the folks who were reluctant due to Surgisphere.
That was literally a form of 'last case' bias that so often plagues surgeons and leads to bad decision making
It was also an irrational take home lesson as surgisphere CLEARED & not CAUGHT by peer review, lets not forget
That was literally a form of 'last case' bias that so often plagues surgeons and leads to bad decision making
It was also an irrational take home lesson as surgisphere CLEARED & not CAUGHT by peer review, lets not forget
The inference for clinical care is EXACTLY as detailed in PR
Table 1 confirms the trial is broadly representative of the UK
My take home message is we have a critical appraisal crisis in medicine
When errors occur
9/10 the error is accepting a result that is problematic
1/10 (as here) it is unfair cynicism
Both are bad & deadly.
If we teach better, we can improve both
That means less Kreb cycle
When errors occur
9/10 the error is accepting a result that is problematic
1/10 (as here) it is unfair cynicism
Both are bad & deadly.
If we teach better, we can improve both
That means less Kreb cycle
