1/4 Time for a mea culpa. I would like to highlight a serious misinterpretation I did in the past. In 2013 we proposed CD64 as a marker to identify monocyte-derived cells based on CCR2-dependence. Because with high dose of HDM we found CD64int cells in LNs, we called them moDCs.

2/4 Now using single-cell sequencing and pre-cDC transfers we show that cDC2s can acquire a CD64-int profile and acquire many monocyte-associated genes. These are NOT moDCs, although they are indeed CCR2-dependent. Read full story here: https://www.cell.com/immunity/fulltext/S1074-7613(20)30163-1

3/4 This emphasizes that the only real thing you should trust are the data. Please see any of my interpretations in discussions or reviews as an educated guess. Still... When you mess up you should own it, so I sincerely apologize if I have sent people on the wrong track.

4/4 P.S.1: Disclaimer for the next decade: maybe these inf-cDC2s are a hybrid cDC3 subset? Maybe inflammation rewires DC development? Who knows?
P.S.2: Fantastic work of @BosteelsCedric and very grateful to @bart_lambrecht to allow me to set this straight with them. Superb paper!