was supposed to be in Tallinn, Estonia this week for @eapcct

instead spent the morning reading abstracts from the cancelled conference, eating pickles, and drinking beer (ran out of квас)

some highlights follow

https://doi.org/10.1080/15563650.2020.1741981

toxic hyperthermia remains highly fatal according to 5 years of cases from NYCPCC

suboptimal sedation, many don't get ice baths, lots of room to improve

@ETontox @MarkKSuMD1 @ToxNyu @bobhoffmd

SILENT is a feared complication of lithium intoxication but often occurs in pts w/ comorbidities, definition is vague, unclear if preventable

these authors couldn't demonstrate histopathological changes in rats in models of acute, acute on chronic, or chronic toxicity

portal embolism (and caustic injury) common with hydrogen peroxide ingestion in this case series, % not reported, HBO performed a few times

unclear what prognostic value it has, all emboli resolved, pts did well

your scheduled reminder that every tox conference is a distillation of immense human suffering

absolute horror story

decontaministas will love this - quantifiable organophosphates in GI lavage effluent after overdose, many >6 hours after event

surprise! clinical outcomes not reported

cool pre/post study of a policy intervention (labelling antitussives) on pediatric antitussive exposures at a PCC

seems to work but herbal exposures went up a little

endemic botulism (mostly type C) is a cause for recurring mass die-offs in Italian waterfowl

if you can get colchicine concentrations at your shop (??) in an overdose with known time of ingestion, there may eventually be a nomogram that can help (very early stages, retrospective cohort, missing data)

no surprise, many who are admittted to ICU are sick and die

mass thallium poisoning due to intentionally poisoned office water cooler

russia

just read the whole thing

i think this is an RCT of L-carnitine vs standard care for pts admitted w/ VPA overdose??

if so, the title probably undersells importance of findings

L-carnitine -> shorter hospital LOS, faster VPA and NH3 eliminattion

need the full paper

baths salts in Taiwan are sold and consumed as powder sachets called "toxic milk tea" and "toxic milk tea"

same Paris group that measured colchicine concentrations found plasma methadone concentrations in pts admitted to ICU for overdose poorly predicts mental status and ventilation

treat the pt not level etc

trying to be positive this thread but conclusions of "study" are ridiculous

rapid opioid detox abandoned in US due to ++ complications

apparently the practice remains standard in Lithuania: in here >50% lost to follow-up, of 15 that did return 7/15 back on opioids

there's truth to the saying:

"never microwave hydrochloric acid with thiodiglycol"