Let's talk about the preliminary results of our #UnidosEnSalud study. These are PCR results, not serology results! We were aiming to test everyone in one census tract, but ended up testing many others as well:

We tested ~55% of the residents in our target census tract, comprising approx 57% of households. We learned a lot about building trust with the community to bring people out; we utilized door knocking/canvassing, phone banking, and radio ads. Media coverage also huge!

Why did people avoid testing? Fear of engaging in testing -- some uncomfortable with the setting or being around so many people; privacy concerns; fear of being tracked by govt agencies, and fear of stigma re: testing positive. Some homebound. Also it was hot out!

Overall PCR+ prevalence in the census tract was 2.1%. People who worked in the tract had a PCR+ prev of 6.1%. We expanded testing on the last day and only 1.4% of those residents tested positive.

Guess what? If you can't work from home, you are much more likely to be PCR+.

And the disparities in who can & can't work from home are striking. Note 0/981 caucasians with infection! In the mission, Hispanic/Latinx individuals at highest risk. Note also the M/F ratio of PCR+ indviduals.

Lower income & bigger household also associated with PCR+. Again, if you can't afford to stay home, you are at higher risk of infection. & with bigger household, difficult to appropriately isolate. All kids w/infxn in this study lived with an adult who was also positive

We asked people 3x if they had sx (twice via survey, once at front of line) to triage to appropriate tent. So I trust our data on reported sx. Still, 53% of PCR+ participants reported no symptoms -- are they early in their course or true asymptomatic cases? Will need to f/u.

Here's something that's not getting enough press -- we aren't simply delivering the results to participants. We have teams to help educate about the illness, provide supplies, and link to care. Information without followup does not provide the same benefit to community.

It is not fair that our essential workers suffer from this disease while those with means can stay at home and avoid it. We must learn how to respond to these health inequities & work to stop transmission for the benefit of everyone in the community.

I want to thank @carina_marquez for trusting me to run a study site w/ @FrancescoDSergi, @UCSF_HIVIDGM for dreaming big and bringing testing to the Mission, @czbiohub for PCR testing, the Latino Task Force & all of the volunteers who helped us pull this off. It takes a village.

And this is only the beginning! Stay tuned for more detailed data analysis. And eventually -- serology results! Thanks also to @bgreenhouse1 who helped design this study and our lab who processed all of the blood samples before sending along to Abbott.