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1/5 Smoking Bat points to WIV again!
Thanks @CarltheChippy update from Bill Gallagher claims to have identified source of spike protein in SARS-COV-2 as Bat Coronavirus HKU9 isolated from a Rousettus fruit bat in Guangdong province in 2011.
http://virological.org/t/tackling-rumors-of-a-suspicious-origin-of-ncov2019/384/5 https://twitter.com/bicidiario/status/1256695599786864644
Thanks @CarltheChippy update from Bill Gallagher claims to have identified source of spike protein in SARS-COV-2 as Bat Coronavirus HKU9 isolated from a Rousettus fruit bat in Guangdong province in 2011.
http://virological.org/t/tackling-rumors-of-a-suspicious-origin-of-ncov2019/384/5 https://twitter.com/bicidiario/status/1256695599786864644
2/5 Remember @Baric_Lab 2015 patent?
"present invention provides compositions & methods comprising a chimeric coronavirus spike protein."
It was based on experiments with same bat virus identified:
BtCoV.HKU9.2
BtCoV.HKU9.1
BtCoV.HkU9.3
BtCoV.HKU9.4
https://patentimages.storage.googleapis.com/e9/b2/98/15d4808eff87c9/WO2015143335A1.pdf
"present invention provides compositions & methods comprising a chimeric coronavirus spike protein."
It was based on experiments with same bat virus identified:
BtCoV.HKU9.2
BtCoV.HKU9.1
BtCoV.HkU9.3
BtCoV.HKU9.4
https://patentimages.storage.googleapis.com/e9/b2/98/15d4808eff87c9/WO2015143335A1.pdf
"We believe that future studies should investigate coinfections in specific bat cell lines using a coronavirus similar to Ro-BatCoV HKU9 & the relevant orthoreoviruses from which it will be possible to reveal more of the underlying basis of heterologous coronavirus recombination"
That's from: "A Bat-Derived Putative Cross-Family Recombinant Coronavirus with a Reovirus Gene" by Edward C. Holmes, George F. Gao et al https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038965/
5/5 HKU9 used with ELISA assay to test serum of local residents by Zhengli Shi & Peter Daszak in 2019
"Human-animal interactions & Bat coronavirus spillover potential among rural residents"
Wei Zhang & Ning Wang from WIV conducted the serological testing
https://www.sciencedirect.com/science/article/pii/S2590053619300308?via%3Dihub#!
"Human-animal interactions & Bat coronavirus spillover potential among rural residents"
Wei Zhang & Ning Wang from WIV conducted the serological testing
https://www.sciencedirect.com/science/article/pii/S2590053619300308?via%3Dihub#!
Someone on this thread posted this paper today,
in my opinion it is a very interesting paper co-authored by George Gao in 2016
A Bat-Derived Putative Cross-Family Recombinant Coronavirus with a Reovirus Gene
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005883
Does anyone else find it curious?
in my opinion it is a very interesting paper co-authored by George Gao in 2016
A Bat-Derived Putative Cross-Family Recombinant Coronavirus with a Reovirus Gene
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005883
Does anyone else find it curious?
Images of Interest (1) from WIV Paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178081/
3/5 HKU9 was experimented with at Leiden lab Netherlands in 2009 as one of a selection of 25 sequences representing virus species diversity (C. Lauber and A.E. Gorbalenya, unpublished) was used for phylogenetic analyses https://pdfs.semanticscholar.org/2a4a/b78d1f7a4779d30183857fee820d6f686c4d.pdf
7. Resarch carried out by Zheng Li Shi's team at WIV "Quantitative PCR revealed that the intestinal tract was the main infection site of BatCoV HKU9 and GCCDC1, but HKK9 was also detected in the heart, kidney and lung tissues of individual bats. "
