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1/4 Interesting: A wet lab study from Germany suggests that some degree of limited background immunity against #COVID19 may exist in the population (~1/3 of their healthy donor sample) due to previous infections with other "common cold" coronaviruses. https://bit.ly/3cKIyJE
2/4 The study hypothesizes that this may be a factor related to severity of SARS-CoV-2 infections and may help to explain the high prevalence of nonsymptomatic or mild infections among younger people and kids (because they get a "common cold" more often).
3/4 The study calls for more data to understand cross-reactive (partial) immunity across coronaviruses better -> important for risk evaluation, patient monitoring, vaccine development, and better, more efficient strategies to combat #Covid19.
4/4 Here is the preprint of the actual study: https://doi.org/10.1101/2020.04.17.20061440
