Ioannidis is a fucking snowflake. He's made a career out of pointing out the methodological flaws in other peoples' work and complaining about overhype, but goes crying about being the victim when his deeply flawed and overhyped work comes under the same scrutiny. https://twitter.com/CT_Bergstrom/status/1253822258692284416

And he committed one of the cardinal sins of science - deciding on the answer before he did the experiment