Now this is really interesting...
The claim on this ice-cream is both correct and completely - dangerously - wrong!
Eating fructose does indeed lower blood glucose mass than eating glucose (or sucrose - which is 50% glucose anyway)
BUT...
The claim on this ice-cream is both correct and completely - dangerously - wrong!
Eating fructose does indeed lower blood glucose mass than eating glucose (or sucrose - which is 50% glucose anyway)
BUT...
The reason it doesn’t raise blood glucose is that fructose cannot be converted to glucose
Indeed it feeds into your metabolism below the regulated step of glycolysis (PFK) and can’t go to glycogen stores or anywhere else...
So the minute you eat it, it has to be used
Indeed it feeds into your metabolism below the regulated step of glycolysis (PFK) and can’t go to glycogen stores or anywhere else...
So the minute you eat it, it has to be used
And that means converted to acetyl-CoA immediately
And if you are already energy replete? (NAD pool fully reduced)? Then there’s no choice but to direct that excess acetyl-CoA to fatty acid synthesis
If you don’t the CoA shuttle gets gummed up and there’s no free NAD
And if you are already energy replete? (NAD pool fully reduced)? Then there’s no choice but to direct that excess acetyl-CoA to fatty acid synthesis
If you don’t the CoA shuttle gets gummed up and there’s no free NAD
So you turn Frank’s ice cream to fat
Sure blood glucose didn’t spike and no pressure on your pancreas. But instead you have turned ice cream into adiposity. Not exactly a healthy trade
Sure blood glucose didn’t spike and no pressure on your pancreas. But instead you have turned ice cream into adiposity. Not exactly a healthy trade
So if you were thinking of buying Frank’s ice cream because of the health claim on the lid - DON’T
Carbs are bad, free sugars are worse - but FRUCTOSE IS WORST OF ALL
Carbs are bad, free sugars are worse - but FRUCTOSE IS WORST OF ALL
And if you prefer proof to theory - look at the effect of fructose in the @RxCelerate model of NASH
Adding 2% fructose to the drinking water of rodents causes fatty liver. 2% glucose has no such effect
Adding 2% fructose to the drinking water of rodents causes fatty liver. 2% glucose has no such effect