Thread

Amazing at this point how little we know about #coronavirus:

1. We have a range of R0 from 2.0 to 5.7; that is a massive range.

2. Do we know if asymptomatic people are shedding culturable living virus that infects others or are they just shedding RNA?

1/n

3. Do antibodies mean immunity?

4. How long does immunity last?

5. What is a safe distance? 6 feet? 20 feet? Being on the international space station?

6. How many people have been infected?

7. Why do some people develop cytokine storm while others don't?

2/n

8. What is the infection fatality rate? (odds of dying if you have either a symptomatic or asymptomatic infection)

9. Just how much higher is it than the flu?

3/n

10. We have not nailed down the capacity for aerosolized spread, say in ventilatory ducts & what do we need to do to disinfect those and other surfaces.

11. Do antivirals work?

12. Will a vaccine provide durable protection?

So many more questions as well ...