Q: Why is there an ~20-30% false negative rate with the PCR https://abs.twimg.com/emoji/v2/... draggable="false" alt="🧬" title="DNA" aria-label="Emoji: DNA"> test for #SARS_CoV2 https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦠" title="Microbe" aria-label="Emoji: Microbe">?
A: Mostly due to sampling as explained by @PSampathkumarMD @MayoClinic
Thread 1/2 https://www.news18.com/news/world/many-people-who-have-tested-negative-for-covid-19-might-actually-have-it-warn-scientists-2573267.html">https://www.news18.com/news/worl...
1. The nasopharynx is a tricky place to get a sample from
2. The virus https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦠" title="Microbe" aria-label="Emoji: Microbe"> may have already passed from the upper to the lower respiratory system. (ie a sputum sample would be a better testing specimen
2/2
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