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Earlier this week the medical world was rocked by the hypothesis of virologist Dr. Jurgen Rissland that whisky can protect against COVID-19 (cc: @NobelPrize)
As with many claims made in healthcare these days, this postulate requires vigorous efforts at validation
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As with many claims made in healthcare these days, this postulate requires vigorous efforts at validation
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It would be totally irresponsible to apply this practice at the population level without first conducting a clinical trial.
So #medtwitter went to work
Presenting: WICkED (Whisky agaInst Coronavirus Exposure in Doctors) [acronym credit: @BenWestphalen]
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So #medtwitter went to work
Presenting: WICkED (Whisky agaInst Coronavirus Exposure in Doctors) [acronym credit: @BenWestphalen]
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Phase I requires brave volunteers willing to establish the dose-limiting toxicity.
Let McConaughey show you how it& #39;s done ...
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Let McConaughey show you how it& #39;s done ...
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This is the way ...
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And then, bingo! DLT
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Now on to phase II. I& #39;m an Islay stan but I think it& #39;s important to recognize that some people prefer non-peaty malts and they shouldn& #39;t be punished for being wrong, so I& #39;ve built cross-over into the schema. It was only ethical:
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And finally, the all-important phIII, where we& #39;ll put the peat to the test vs. hydroxychloroquine.
As @VPrasadMDMPH notes there is no excuse for avoiding a hard endpoint during a crisis like this so the primary outcome will be OS (Overall Sobriety).
Sláinte, my friends!
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As @VPrasadMDMPH notes there is no excuse for avoiding a hard endpoint during a crisis like this so the primary outcome will be OS (Overall Sobriety).
Sláinte, my friends!
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