My understanding is the commercial antibody test has specificity issues. California dept public health is working with several partners to get an appropriate test. 1
Remember, sensitivity and specificity matter as does prevalence in population tested. If community prevalence is 6% then test with sensitivity of 95%/specificity 98% has + predictive value of only 75%. If prevalence is 10% then it is 84%. 2
So it seems like the commercial antibody test for the general public who have not tested positive by PCR could cause a lot of confusion and lead some people to think they are protected. Also, we don’t even know what level of protection antibodies confer or for how long. 3.
I’m a big fan of the California Department of Public Health and when they say the antibody test is ready for the public I will listen. 5
I understand the confusion when some hospitals are testing people for antibodies to donate plasma, but that is not the commercial test that is available. 6
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