ZINC
THE CONFOUNDING VARIABLE IS ZINC
GOD FUCKING DAMMIT HOW IS THIS NOT PROMULGATED YET https://twitter.com/realchrishynes/status/1247657897754079232
THE CONFOUNDING VARIABLE IS ZINC
GOD FUCKING DAMMIT HOW IS THIS NOT PROMULGATED YET https://twitter.com/realchrishynes/status/1247657897754079232
here's the fucking deal
to replicate a study where HCQ showed high promise, make sure pts/subjects consume a diet high in zinc, or, like, supplement
to replicate a study where HCQ was nearly ineffective, make sure to do the opposite
to replicate a study where HCQ showed high promise, make sure pts/subjects consume a diet high in zinc, or, like, supplement
to replicate a study where HCQ was nearly ineffective, make sure to do the opposite
layman tldr
—Zn cockblocks *COV2's replication game in the cytosol
—normally v little Zn there; most extracellular
—HCQ: "zinc ionophore" (pulls Zn into cell)
but:
—Zn cockblocks *COV2's replication game in the cytosol
—normally v little Zn there; most extracellular
—HCQ: "zinc ionophore" (pulls Zn into cell)
but:
—old ppl often low in Zn
—also, amerifat diet generally: too much Cu vs lowish Zn
—take a guess whether US hospital food is any better
—note Zn doesn't accumulate. not fat-soluble. extracellular zinc can therefore vary widely day-to-day
—also, amerifat diet generally: too much Cu vs lowish Zn
—take a guess whether US hospital food is any better
—note Zn doesn't accumulate. not fat-soluble. extracellular zinc can therefore vary widely day-to-day
bonus fact
the best, widely-available OTC zinc ionophore is quercetin. if you were MY patient i'd recommend you supplement Zn & quercetin during this time, so that IF you contract C19
—ensures low viral load onset
—you'll be set so if you need hospitalization, the HCQ will work
the best, widely-available OTC zinc ionophore is quercetin. if you were MY patient i'd recommend you supplement Zn & quercetin during this time, so that IF you contract C19
—ensures low viral load onset
—you'll be set so if you need hospitalization, the HCQ will work
don't go nuts
target ~60mg Zn & ~1g quercetin daily, divided in 2 or 3 doses
note 1: get quercetin either with bromelain included, or acquire separately. quercetin isn't very orally bioavailable elsewise
note 2: Zn as picolinate or monomethionine, bioavailability reasons again
target ~60mg Zn & ~1g quercetin daily, divided in 2 or 3 doses
note 1: get quercetin either with bromelain included, or acquire separately. quercetin isn't very orally bioavailable elsewise
note 2: Zn as picolinate or monomethionine, bioavailability reasons again