Latest @CDCMMWR looks at paediatric cases of #COVID19 in the US (n=2,572). Findings:
Relatively few hospitalisations
Fever, cough, SOB less prominent than adults
Severe outcomes possible, 3 deaths this dataset
Importance of mild/atypical/asymptomatic in transmission
Relatively few hospitalisations
Fever, cough, SOB less prominent than adults
Severe outcomes possible, 3 deaths this dataset
Importance of mild/atypical/asymptomatic in transmission
Kids (<18) 1.7% US cases
Fever, cough, SOB 73% (93% adults)
5.7% hospitalised
Median age 11y, one third in 15-17yo, 27% in 10-14y, 15% <1y
Majority (where info known, only 7.2% of the cohort), vast majority (91%) household/community transmission
#COVID19
Fever, cough, SOB 73% (93% adults)
5.7% hospitalised
Median age 11y, one third in 15-17yo, 27% in 10-14y, 15% <1y
Majority (where info known, only 7.2% of the cohort), vast majority (91%) household/community transmission
#COVID19
Combined w hosp/ICU data where known, 77% admissions and all ICU cases had at least 1 comorbidity
Among non-hospitalised cases where this data was available, 12% had comorbidities
5/15 ICU admissions in kids <1y
57% of all paed #COVID19 cases male, ? biologic factors
Among non-hospitalised cases where this data was available, 12% had comorbidities
5/15 ICU admissions in kids <1y
57% of all paed #COVID19 cases male, ? biologic factors
Dataset has lots of omissions, incomplete info, but authors say valuable preliminary insights largely accord w other paed #COVID19 studies:
Illness looks different and more mild in kids, ? important in transmission
More severe in infants (<1y) & those with comorbidities
Illness looks different and more mild in kids, ? important in transmission
More severe in infants (<1y) & those with comorbidities
Hospitalisation data only available in around 1/3 of cases but estimates 5.7-20% (10-33% adults) require admission, 0.58-2% (1.4-4.5% adults) ICU
Rates highest in kids <1y (59 cases in set, 5 requiring ICU)
3 deaths but reviews ongoing as to whether #COVID19 the cause
Rates highest in kids <1y (59 cases in set, 5 requiring ICU)
3 deaths but reviews ongoing as to whether #COVID19 the cause
Full paper here: https://www.cdc.gov/mmwr/volumes/69/wr/mm6914e4.htm?s_cid=mm6914e4_w
#COVID19
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#COVID19
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Fever in 56% (71% adults) cough in 54% (80%) SOB 13% (43%)
Myalgia, sore throat, headache & diarrhoea also less common than in adults
1.3% were asymptomatic, another 68% did not report cardinal sx but info incomplete so not able to say if truly asymptomatic
#COVID19
Myalgia, sore throat, headache & diarrhoea also less common than in adults
1.3% were asymptomatic, another 68% did not report cardinal sx but info incomplete so not able to say if truly asymptomatic
#COVID19
As with adults, importance of underlying conditons
This data available for 345 cases; 23% had at least one
Chronic lung disease including asthma (n=40), CVD (25), immunosuppression (10) most common
#COVID19
This data available for 345 cases; 23% had at least one
Chronic lung disease including asthma (n=40), CVD (25), immunosuppression (10) most common
#COVID19