Hearing from two physicians (these are not run of the mill, very academic and widely informed about pathology and pharmacology): 1) There is a good chance of serious morale issues among health care providers as the virus continues its rampage. You become physician/nurse only if
you are 1 of those high energy types. But the load is straining them and will only go up. Further PPE shortages mean they are facing greater personal risk like a soldier sent to the front poorly armed. Combination could get to the system to the point of breaking. Probably Iran,
Spain, Italy have already seen this and the consequences are seens. 2) We agreed that vaccines are not at all on the immediate horizon and while a successful 1 might eventually come we are currently far from one. We understand the immunological effects of this virus rather poorly
3) There is little we can do right now short of throwing the kitchen sink at it from chloroquine, angiotensin converting enzyme binders, to other crazy stuff in the hope something sticks. A good point they made was that the new drugs are probably in similar league as vaccines as
they are going to take a long time to develop to use safely enough -- yes it is easily possible to harm the patient as much as virus with these untested molecules. But biological conflict works that way: throw the kitchen sink -> something sticks -> natural selections fixes it.
4) A common problem to physicians, scientifically educated and layfolks alike is avoiding the virus from common activities like collecting mail/packages, groceries etc. Noted that they are following similar strategy: limit visits for these ~1 week. Wash the produce thoroughly, if
possible 1st with soap &then water before refrigerating. Wipe cartons with disinfectants. Keep aside dry stuff for 2-3 days before storing. Agreed that risk is likely low from these sources but the visit to the grocery itself poses some risk because not every1 distances properly
Already heard of death of grocery workers in the neighboring counties in the chain I use. If this mounts supplies could be in danger. 5) Even among the well informed academic physicians there are gaps in the knowledge of the evolutionary history of coronaviruses which translates
into improper understanding of the enzymology and biochemistry of the viral proteins. Especially what are the commonalities differences of SARS-CoV-1, SARS-CoV-2, MERS-CoV and other CoVs at a molecular level. Not all catalyze the same set of reactions inside the cell. This is
important because it actually informs what drugs might work and what drugs can be tried out. Had to do some education in this regard.
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