As clinical trials for #COVID19 ramp up the term "breakthrough" is likely to be used more and more frequently. Please read this thread to understand why that may be problematic.

TL;DR - I'll just quote The Princess Bride: "I do not think that word means what you think it means." https://twitter.com/alecgaffney/status/1245541640577732613
The thread also mentions that the FDA has 22 programs they're likely to use to get #COVID19 therapies through the testing process. That...is a lot & I don't know how or whether representative populations are equitably considered across these mechanisms.

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