Peter Openshaw explains the local and systemic inflammatory responses in #Covid19 that drive the clinical presentation. While Respiratory failure is the main issue, cardiac failure is the next most common issue in #Covid19.

@ImperialNHLI @imperialcollege @TheBHF

ISARIC was setup following major viral outbreaks with the concept of ramping up if another pandemic occurred. This is now supporting large studies across the world with standardised protocols - makes it easier to cross correlate data. #ImperialCovidWebinar

ISARIC has allowed rapid recruitment of UK patients: huge numbers very quickly.
#ImperialCovidWebinar

Prognosis is related to age and associated co-morbidity. #ISARIC
#ImperialCovidWebinar