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Scientists, statisticians and innovators along with physicians (and not clinicians focused in one area alone) should indeed be the guiding force behind policy decisions. India’s advisory seems to have skipped the process and jumped to conclusions https://twitter.com/ani/status/1242802676435283970?s=21 https://twitter.com/rfonsi1/status/1243538596679823364
https://twitter.com/ani/status/1242802676435283970?s=21 We don’t have strong enough evidence for giving it to these two groups either. https://twitter.com/ANI/status/1242802676435283970
https://twitter.com/spkalantri/status/1242626752326725632?s=21 https://twitter.com/spkalantri/status/1242626752326725632
https://twitter.com/schneiderleonid/status/1242889208651448322?s=21 https://twitter.com/schneiderleonid/status/1242889208651448322
Why do Didier Raoults of the world exist? The answer lies in the “publish or perish” rewards driven culture of academia, that doesn’t value the learning in negative results equally, though it should. Science is a process. This piece sheds some more light. https://www.vox.com/2016/7/14/12016710/science-challeges-research-funding-peer-review-process
It is alright for arguments and stances to change in light of emerging evidence. It is not alright if the pre-requisite for such a change is that arguments must keep pace with the decisions of bosses one shares political leanings with. End.
https://twitter.com/raoult_didier/status/1243651596808003587?s=20
Hit translate to see the thread and replies. Dramatic drops in viral loads emphasized, but mention of improved clinical correlates missing in that particular tweet. Also
Hit translate to see the thread and replies. Dramatic drops in viral loads emphasized, but mention of improved clinical correlates missing in that particular tweet. Also
The original point stands — why issue such an advisory? Why not show respect for the process? This is not the last pandemic. The covid 19 crisis does give us an opportunity to seriously rethink our systems and plan ahead. (Not claiming this thread ends here).
This is an important point to note. The “craze” over HCQS’ putative efficacy and safety in treating #COVID was apparently kickstarted by a letter to the editor. https://twitter.com/siddhartha_kar/status/1243885105497673728?s=20
Indian API (Active Pharmaceutical Ingredient) makers to boost output of antimalarial drugs found effective against covid-19, says the headline. Screenshots attached stating companies ready to ramp up production three to five fold. Dated Mar 23/2020.
Wonder if we will see more and more trials featuring HCQS now.
https://twitter.com/michaelcoudrey/status/1243779158737440768?s=21 https://twitter.com/MichaelCoudrey/status/1243779158737440768
This guy is an entrepreneur and activist. He quotes India’s advisory to use HCQS for its HCWs. One can’t help wonder if he likes the idea of the advisory enough to ask for it to be replicated everywhere else 
https://twitter.com/michaelcoudrey/status/1243788862838566917?s=21 https://twitter.com/michaelcoudrey/status/1243788862838566917
https://twitter.com/michaelcoudrey/status/1243788862838566917?s=21 https://twitter.com/michaelcoudrey/status/1243788862838566917
https://twitter.com/anupsoans/status/1244306742671884291?s=21 https://twitter.com/anupsoans/status/1244306742671884291
https://twitter.com/sabinabasha/status/1244328233882927104?s=21 https://twitter.com/SabinaBasha/status/1244328233882927104
Fighting misinformation is hard. A thread by the brilliant Noah Haber who was asked by a friend to review the HCQS/Azithromycin Didier Ranoult trial https://twitter.com/NoahHaber/status/1244348188166742016?s=20
Another important point. https://twitter.com/otorhinosaur/status/1244850801501179904?s=20
And now, the ultimate : https://twitter.com/rdivia/status/1245001501270929408?s=20
The official document says the advisory is based on uncontrolled clinical trials. OKAY.
Another tweet in this thread mentions moderate improvement in non severe #Covid_19 cases post HCQS admin, not so in severe cases. https://twitter.com/gaetanburgio/status/1245474991644139520?s=21 https://twitter.com/gaetanburgio/status/1245474991644139520
