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Colleagues at Oxford are working towards the much needed vaccine.
They are looking for 510 volunteers. If you live in the area consider applying as a volunteer for this vaccine trial.
I applied earlier today. https://twitter.com/UniofOxford/status/1243508875225108480
They are looking for 510 volunteers. If you live in the area consider applying as a volunteer for this vaccine trial.
I applied earlier today. https://twitter.com/UniofOxford/status/1243508875225108480
If you are interested in details about the trial, the researchers published this very readable document about it https://covid19vaccinetrial.web.ox.ac.uk/files/cov001pisv2018mar2020localisedpdf
A key passage on the basic idea of the vaccine is below.
A key passage on the basic idea of the vaccine is below.
Update on this.
They picked me as a potential candidate for this vaccine trial.
Just now I did a big health check with them.
And they explained in detail the potential risks of a vaccine trial.
I was impressed by the research team and am happy I could contribute a datapoint.
They picked me as a potential candidate for this vaccine trial.
Just now I did a big health check with them.
And they explained in detail the potential risks of a vaccine trial.
I was impressed by the research team and am happy I could contribute a datapoint.
It's great to see how far the Oxford team has already come.
Also because they started early. The work on this potential COVID-19 vaccine started on Friday 10th January.
http://www.ox.ac.uk/news/2020-03-27-oxford-covid-19-vaccine-programme-opens-clinical-trial-recruitment#
The first human trials at Oxford will begin the day after tomorrow.
Also because they started early. The work on this potential COVID-19 vaccine started on Friday 10th January.
http://www.ox.ac.uk/news/2020-03-27-oxford-covid-19-vaccine-programme-opens-clinical-trial-recruitment#
The first human trials at Oxford will begin the day after tomorrow.
Whether the Oxford vaccine is effective will only be determined in the trial that just started.
But to not lose time – in the case we are fortunate and this vaccine is indeed effective – the Oxford vaccine is *already* being manufactured now. https://www.europeanpharmaceuticalreview.com/news/117636/uk-covid-19-vaccine-candidate-to-be-manufactured-at-seven-outsourced-sites/
But to not lose time – in the case we are fortunate and this vaccine is indeed effective – the Oxford vaccine is *already* being manufactured now. https://www.europeanpharmaceuticalreview.com/news/117636/uk-covid-19-vaccine-candidate-to-be-manufactured-at-seven-outsourced-sites/
New research results on the vaccine candidate ('ChAdOx1') of the trial in Oxford:
https://www.biorxiv.org/content/10.1101/2020.05.13.093195v1
A single vaccination prevented pneumonia in rhesus macaques that were exposed to the coronavirus.
This is a promising finding for the ongoing human trials!
https://www.biorxiv.org/content/10.1101/2020.05.13.093195v1
A single vaccination prevented pneumonia in rhesus macaques that were exposed to the coronavirus.
This is a promising finding for the ongoing human trials!
Another update on the Oxford vaccine trial.
http://www.ox.ac.uk/news/2020-05-22-oxford-covid-19-vaccine-begin-phase-iiiii-human-trials
The trial is now entering phases 2 and 3 and is expanding the trial to 10,200 people. It will now also include older adults since they are the group with the highest mortality risk from COVID19.
http://www.ox.ac.uk/news/2020-05-22-oxford-covid-19-vaccine-begin-phase-iiiii-human-trials
The trial is now entering phases 2 and 3 and is expanding the trial to 10,200 people. It will now also include older adults since they are the group with the highest mortality risk from COVID19.
If you live in the UK and you are at home in one of these locations you can volunteer to take part in the vaccine trial.
Here you can sign up: https://covid19vaccinetrial.co.uk/participate-trial
Here you can sign up: https://covid19vaccinetrial.co.uk/participate-trial
The researchers at Oxford are now collaborating with the Federal University of São Paulo to expand the COVID-19 vaccine trial to Brazil.
They will recruit 2,000 volunteers to take part of the trials there. https://www.reuters.com/article/us-health-coronavirus-vaccine-brazil-idUSKBN23A31M
They will recruit 2,000 volunteers to take part of the trials there. https://www.reuters.com/article/us-health-coronavirus-vaccine-brazil-idUSKBN23A31M
The Lancet will publish the first results from Oxford's COVID-19 vaccine trial on Monday.
What the newspapers are reporting so far is encouraging. “It produces both a T cell and an antibody response."
https://www.hindustantimes.com/science/double-defence-oxford-university-covid-19-vaccine-s-early-trial-results-raise-hopes/story-fr87wUMFFW5GGWzRh64A0H.html
Looking forward to next Monday!
What the newspapers are reporting so far is encouraging. “It produces both a T cell and an antibody response."
https://www.hindustantimes.com/science/double-defence-oxford-university-covid-19-vaccine-s-early-trial-results-raise-hopes/story-fr87wUMFFW5GGWzRh64A0H.html
Looking forward to next Monday!
The first results are out. They are still preliminary and it's still a very long way, but the results published just now suggest that the Oxford vaccine is safe and that it induces the desired immune reaction.
Here is the paper: http://TheLancet.com/lancet/article/s0140-6736(20)31604-4
Here is the paper: http://TheLancet.com/lancet/article/s0140-6736(20)31604-4
The COVID-19 vaccine trial at Oxford is now continuing. I just got my booster shot.
If you want to take part in this vaccine trial as well, here you can apply to be a volunteer: http://covid19vaccinetrial.co.uk/home
If you want to take part in this vaccine trial as well, here you can apply to be a volunteer: http://covid19vaccinetrial.co.uk/home
2.4 billion ordered doses! The world is really betting on the Oxford vaccine to work.
[from https://www.economist.com/briefing/2020/11/14/an-effective-covid-19-vaccine-is-a-turning-point-in-the-pandemic]
![2.4 billion ordered doses! The world is really betting on the Oxford vaccine to work.[from https://www.economist.com/briefing/2020/11/14/an-effective-covid-19-vaccine-is-a-turning-point-in-the-pandemic]](https://pbs.twimg.com/media/EmzkT_HXUAAly-Q.png "2.4 billion ordered doses! The world is really betting on the Oxford vaccine to work.[from https://www.economist.com/briefing/2020/11/14/an-effective-covid-19-vaccine-is-a-turning-point-in-the-pandemic]")
[from https://www.economist.com/briefing/2020/11/14/an-effective-covid-19-vaccine-is-a-turning-point-in-the-pandemic]
New results from the Oxford vaccine trial just got published in The Lancet.
It studied whether the immune response provoked by the vaccine is as good in older patients as in younger patients –– very important since COVID is a high risk for older people.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32466-1/fulltext
It studied whether the immune response provoked by the vaccine is as good in older patients as in younger patients –– very important since COVID is a high risk for older people.
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32466-1/fulltext
The early data on the COVID vaccine developed here at @UniofOxford is out!
• In the standard dose it is 70% effective.
• Two-dose-regimens suggest that it could be 90%.
• There were zero hospitalised or severe cases in those who received the vaccine. https://www.ox.ac.uk/news/2020-11-23-oxford-university-breakthrough-global-covid-19-vaccine
• In the standard dose it is 70% effective.
• Two-dose-regimens suggest that it could be 90%.
• There were zero hospitalised or severe cases in those who received the vaccine. https://www.ox.ac.uk/news/2020-11-23-oxford-university-breakthrough-global-covid-19-vaccine
The Oxford vaccine has several big advantages:
• It can be stored at fridge temperature (2-8°C).
• It is easily administered in existing healthcare systems.
• And it can be distributed using existing logistics.
• It can be stored at fridge temperature (2-8°C).
• It is easily administered in existing healthcare systems.
• And it can be distributed using existing logistics.
What's extremely positive is that manufacturing of the vaccine has been going on at a very large scale in over 10 countries.
They took a risk to start production before the trial results were in. If they were negative it would have had to be discarded –– but that's not the case!
They took a risk to start production before the trial results were in. If they were negative it would have had to be discarded –– but that's not the case!
All the above points are especially positive for people in low- and middle-income countries.
A key element of Oxford’s partnership with @AstraZeneca is to make a vaccine that is available and useful for people in poorer countries and we now made a massive step in that direction.
A key element of Oxford’s partnership with @AstraZeneca is to make a vaccine that is available and useful for people in poorer countries and we now made a massive step in that direction.
