Hi, if you know of a charity offering a well-thought-out, system-level strategy to address #COVID19, tweet it at me. Examples: innovations to increase ventilator production, secure food supply chains, advocate smart policy, protect homeless people. I'll share as they come.
This fund from @CDCFound supports @CDCgov's efforts to help state and local health departments in the United States with useful things like supplemental funds to purchase reagents for testing and the like. https://www.cdcfoundation.org/coronavirus  (NB: last update was from more than a month ago)
If you're looking for a more grassroots approach, try the Emergent Fund's People's Bailout, which focuses on supporting activists and mutual aid societies particularly in BIPOC communities: https://secure.actblue.com/donate/emergent-peoples-bailout
The @gatesfoundation offers two funds: 1. the Combating COVID-19 Fund which supports vaccine development and health infrastructure in the Global South, and 2. a Therapeutics Accelerator Fund to get non-vaccine treatments to market quickly. https://www.gatesfoundation.org/philanthropypartners/funds/covid-19
The COVID-19 Solidarity Response Fund from @WHO focuses on tracking and building up response capacity in the countries with the poorest public health infrastructure. Activities so far have mostly included sending PPE (masks, etc.) to these countries. https://covid19responsefund.org/faq 
The effective altruist organization @80000Hours, which has been all over this topic for months, offers a roundup of donation recommendations here: https://80000hours.org/articles/covid-19-options-for-donating/. Suggestions include @CGDev in addition to Gates and Hopkins mentioned above.
Also note this, from the article linked above: "If you intend to donate over $200,000, you can get in touch with Jacob Trefethen (ja[email protected]), who is currently making grants in this area." @open_phil has been a leader in funding biosecurity in recent years.
It looks like one of the main efforts to develop an anti-COVID vaccine is being led by @CEPIvaccines, which has raised $690M toward a $2B campaign to accelerate vaccine development and distribution. Amazingly less than some universities' capital campaigns. https://cepi.net/covid-19/ 
If you'd like to fund rapid scientific research on COVID-19, consider supporting Fast Grants. According to the website, "Fast Grants are $10k to $500k and decisions are made in under 48 hours." The funding goes through @tylercowen's Emergent Ventures. https://fastgrants.org 
Medecins Sans Frontieres, aka Doctors Without Borders, is one of the only organizations working to increase COVID treatment capacity at hospitals in the Global South. Its geographic reach includes many countries poorly served by other aid groups. https://www.msf.org/covid-19-depth 
The cash transfer charity @GiveDirectly, mentioned earlier in this thread, has now 1) expanded its US ambitions to a $100M campaign to help 100k families, and 2) launched an international version of its efforts with an initial focus on Nairobi, Kenya: https://www.givedirectly.org/covid-19-international/
You can follow @iandavidmoss.
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