Read on Twitter
I want to try and compile a thread of all medical and public health data, in the next few days. Keeping in mind that some information at this stage is still speculative and not confirmed. Please contribute as you find worthy articles/threads/links.
ONE PERSON linked to over 1000 other cases - unbelievable. And incredible reminder of the need to self isolate IMMEDIATELY, all the more so if you're feeling ill. https://graphics.reuters.com/CHINA-HEALTH-SOUTHKOREA-CLUSTERS/0100B5G33SB/index.html
SARSCoV-2 binds to target cells enzyme ACE2 on epithelial cells of lung, intestine, kidney, and blood vessels. There is increased ACE2 in patients with type 1 or
2 diabetes, who are treated with ACE inhibitors and angiotensin II type-I receptor blockers.
https://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600(20)30116-8.pdf
2 diabetes, who are treated with ACE inhibitors and angiotensin II type-I receptor blockers.
https://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600(20)30116-8.pdf
ACE2 can also be increased by thiazolidinediones
and ibuprofen. Since the virus uses this enzyme to enter the cells, diabetics esp on ACEII or ARBs would be at greater risk. It would also explain why ibuprofen seems to aggravate disease progression and why panadol is recommended.
and ibuprofen. Since the virus uses this enzyme to enter the cells, diabetics esp on ACEII or ARBs would be at greater risk. It would also explain why ibuprofen seems to aggravate disease progression and why panadol is recommended.
Important Update on treatment!!! https://www.pharmaceutical-technology.com/news/fujifilm-favipiravir-covid-19/
However, seems only Japan producing and they have 2 million doses for domestic use. THis needs to become a global public good with mass production at cost or free https://www.theguardian.com/world/2020/mar/18/japanese-flu-drug-clearly-effective-in-treating-coronavirus-says-china
Can anyone confirm that Indian National Task Force on COVID19 has prescribed HCQ for prophylaxis?
https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&cad=rja&uact=8&ved=2ahUKEwio7MbDgrPoAhUoAGMBHTsiDp8QFjABegQIBxAB&url=https%3A%2F%2Fwww.mohfw.gov.in%2Fpdf%2FAdvisoryontheuseofHydroxychloroquinasprophylaxisforSARSCoV2infection.pdf&usg=AOvVaw1NycGa-VncI3XaSBED_nyD
https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&cad=rja&uact=8&ved=2ahUKEwio7MbDgrPoAhUoAGMBHTsiDp8QFjABegQIBxAB&url=https%3A%2F%2Fwww.mohfw.gov.in%2Fpdf%2FAdvisoryontheuseofHydroxychloroquinasprophylaxisforSARSCoV2infection.pdf&usg=AOvVaw1NycGa-VncI3XaSBED_nyD
@JahangirSartaj @smzrz @zfrmrza Trying to verify this. Could have implications for our front line people (health care workers, delivery people, police, etc).
Essential thread on why masks are necessary https://twitter.com/rkhamsi/status/1244659064350670848?s=21
