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Our preprint describing the BarCoder algorithm to generate synthetic PCR signatures is up on @BioArxiv! Thanks to the project team at @CCDC_ChemBio for their hard work and to @doddtra for supporting the work! https://biorxiv.org/cgi/content/short/2020.01.06.896035v1
While applying this algorithm to another project, we have discovered an error in the algorithm code that may result in primers that do not meet the criteria in this preprint. We believe that the wet-lab data are accurate, but future primers generated may not perform properly.
We have reached out to the journal editors and have asked for a hold on publication of the revised article pending a resolution of this issue.
I will update this thread as we address this issue.
