Following the @BBCNewsnight segment on “detransitioners”, here’s some evidence-based research about transition ‘regret’ that @TaviAndPort could have cited...
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Of 162 trans adults, only 1 reported they would choose not to transition again. Another had some regrets but would choose to transition again (0.6% regret rate)
Sex reassignment: outcomes and predictors of treatment for adolescent and adult transsexuals
https://www.cambridge.org/core/journals/psychological-medicine/article/sex-reassignment-outcomes-and-predictors-of-treatment-for-adolescent-and-adult-transsexuals/D000472406C5F6E1BD4E6A37BC7550A4
Sex reassignment: outcomes and predictors of treatment for adolescent and adult transsexuals

Of people undergoing SRS, regret was about 2.2% and there was a significant decline of regret over time.
An analysis of all applications for sex reassignment surgery in Sweden, 1960-2010: prevalence, incidence, and regrets.
https://www.ncbi.nlm.nih.gov/pubmed/24872188
An analysis of all applications for sex reassignment surgery in Sweden, 1960-2010: prevalence, incidence, and regrets.

Research has shown that less than 1% of the 3,398 trans patients who accessed NHS support went on to detransition. @CRichardsPsych
Detransition rates in a national UK Gender Identity Clinic
[pg 139] https://epath.eu/wp-content/uploads/2019/04/Boof-of-abstracts-EPATH2019.pdf
Detransition rates in a national UK Gender Identity Clinic

The most common reason for detransition is the person couldn’t cope with the family and community support they lost and the experiences of transphobia.
Factors predictive of regret in sex reassignment.
https://www.ncbi.nlm.nih.gov/pubmed/9570489
Factors predictive of regret in sex reassignment.
https://www.ncbi.nlm.nih.gov/pubmed/9570489
There are also many incidents of trans people detransitioning to then retransition later on.
I detransitioned because of transphobia, but I always knew I am a woman. Now I'm living as my authentic self - @katieloukhaos
https://inews.co.uk/opinion/comment/i-detransitioned-because-of-discrimination-but-i-always-knew-i-am-a-woman-now-im-living-as-my-authentic-self-502815
I detransitioned because of transphobia, but I always knew I am a woman. Now I'm living as my authentic self - @katieloukhaos

Recognising and supporting trans people who choose a different pathway is crucial, but as @EnbyLawyer importantly stated; we need to make sure that their experiences aren’t cited as a reason to not provide internationally recognised treatment for those trans people who need it. https://twitter.com/BBCNewsnight/status/1199104370446520320