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For those who practice the microbiome religion, we know practically nothing about it yet, Contradictory results are the norm, "L. plantarum reduces the life span of Drosophila These results are apparently at odds with published evidence for beneficial effects of L. plantarum.."
"Overall, our current understanding of the precise relationships between the human gut microbiome and disease remains limited." https://www.nature.com/articles/s41467-017-01973-8
Hmm, the ketogenic diet makes improvements on the microbiome? How if, as the chubby nutritionist say, it's dangerously low in fiber? "Moreover, increased levels of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) were detected..and observed to be microbiota-dependent."
It's barely in the hypothesis generating stage, "Understanding and drawing insight from this literature to establish human microbiome-disease associations for hypothesis confirmation and generation will be critical for scientific discovery going forward".
They haven't even defined all the species yet, "knowledge of individual microbial species is needed to decipher their biological roles. Despite extensive culturing and sequencing efforts, the complete bacterial repertoire of the human gut microbiota remains undefined"
They talk about the microbiome research in terms of "hopes", "However, most importantly, we debate one part of the current knowledge in this field and ask the following question: how should we interpret the numerous hopes, promises and threats?" https://gut.bmj.com/content/67/9/1716
