My first preprint, "Hidden heterogeneity and its influence on dengue vaccination impact," aka https://abs.twimg.com/emoji/v2/... draggable="false" alt="🕵🏼‍♀️" title="Woman detective (mittelheller Hautton)" aria-label="Emoji: Woman detective (mittelheller Hautton)">https://abs.twimg.com/emoji/v2/... draggable="false" alt="📊" title="Balkendiagramm" aria-label="Emoji: Balkendiagramm">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦟" title="Mosquito" aria-label="Emoji: Mosquito">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦠" title="Microbe" aria-label="Emoji: Microbe">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🥵" title="Hot face" aria-label="Emoji: Hot face">https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🥊" title="Boxhandschuh" aria-label="Emoji: Boxhandschuh"> is now @medrxivpreprint! 1/10 https://twitter.com/medrxivpreprint/status/1173701181471956993">https://twitter.com/medrxivpr...

This work in @ndeckinstitute #PerkinsLab w @TAlexPerkins was a big part of my undergrad @NotreDame https://abs.twimg.com/emoji/v2/... draggable="false" alt="🍀" title="Vierblättriges Kleeblatt" aria-label="Emoji: Vierblättriges Kleeblatt">https://abs.twimg.com/emoji/v2/... draggable="false" alt="👩🏼‍🎓" title="Woman student (mittelheller Hautton)" aria-label="Emoji: Woman student (mittelheller Hautton)"> as an @NDBios major https://abs.twimg.com/emoji/v2/... draggable="false" alt="🧬" title="DNA" aria-label="Emoji: DNA">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦠" title="Microbe" aria-label="Emoji: Microbe">https://abs.twimg.com/emoji/v2/... draggable="false" alt="📚" title="Bücher" aria-label="Emoji: Bücher"> 2/10

I also got to present https://abs.twimg.com/emoji/v2/... draggable="false" alt="📈" title="Tabelle mit Aufwärtstrend" aria-label="Emoji: Tabelle mit Aufwärtstrend">https://abs.twimg.com/emoji/v2/... draggable="false" alt="👩🏼‍🏫" title="Woman teacher (mittelheller Hautton)" aria-label="Emoji: Woman teacher (mittelheller Hautton)">versions along the way @KelloggInst and @ASTMH annual meeting in #NOLA https://abs.twimg.com/emoji/v2/... draggable="false" alt="🎺" title="Trompete" aria-label="Emoji: Trompete">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🎷" title="Saxophon" aria-label="Emoji: Saxophon">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🎩" title="Zylinder" aria-label="Emoji: Zylinder">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🎉" title="Partyknaller" aria-label="Emoji: Partyknaller"> w support https://abs.twimg.com/emoji/v2/... draggable="false" alt="💲" title="Fettes Dollarzeichen" aria-label="Emoji: Fettes Dollarzeichen">https://abs.twimg.com/emoji/v2/... draggable="false" alt="✈️" title="Flugzeug" aria-label="Emoji: Flugzeug">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🛏" title="Bett" aria-label="Emoji: Bett">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🙌🏼" title="Raising hands (mittelheller Hautton)" aria-label="Emoji: Raising hands (mittelheller Hautton)"> from @ND_CUSE 3/10

This preprint is about #Dengvaxia, a vaccine known to put ppl who have never had dengue at risk of more severe dengue when they get the virus https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze">https://abs.twimg.com/emoji/v2/... draggable="false" alt="👧🏻" title="Mädchen (heller Hautton)" aria-label="Emoji: Mädchen (heller Hautton)">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦟" title="Mosquito" aria-label="Emoji: Mosquito">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦠" title="Microbe" aria-label="Emoji: Microbe">https://abs.twimg.com/emoji/v2/... draggable="false" alt="⬆️" title="Pfeil nach oben" aria-label="Emoji: Pfeil nach oben">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🌡" title="Thermometer" aria-label="Emoji: Thermometer"> 4/10

We wanted to understand the consequences https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤔" title="Denkendes Gesicht" aria-label="Emoji: Denkendes Gesicht"> of vaccinating a population https://abs.twimg.com/emoji/v2/... draggable="false" alt="💉" title="Spritze" aria-label="Emoji: Spritze"> where some people had lots of dengue before https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦟" title="Mosquito" aria-label="Emoji: Mosquito">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦠" title="Microbe" aria-label="Emoji: Microbe">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🌡" title="Thermometer" aria-label="Emoji: Thermometer">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦟" title="Mosquito" aria-label="Emoji: Mosquito">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🦠" title="Microbe" aria-label="Emoji: Microbe">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🌡" title="Thermometer" aria-label="Emoji: Thermometer"> and others had not https://abs.twimg.com/emoji/v2/... draggable="false" alt="😎" title="Lächelndes Gesicht mit Sonnenbrille" aria-label="Emoji: Lächelndes Gesicht mit Sonnenbrille">. E.g. high-risk and low-risk neighborhoods in a city 5/10

And policy makers! https://abs.twimg.com/emoji/v2/... draggable="false" alt="👩🏽‍💼" title="Woman office worker (mittlerer Hautton)" aria-label="Emoji: Woman office worker (mittlerer Hautton)">https://abs.twimg.com/emoji/v2/... draggable="false" alt="👨🏻‍💼" title="Man office worker (heller Hautton)" aria-label="Emoji: Man office worker (heller Hautton)"> 10b/10

An exciting new addition to this thread, the official published version! Very excited to have had this published in Infectious Disease Modeling. Thanks again to @TAlexPerkins!!

https://doi.org/10.1016/j.idm.2020.09.008">https://doi.org/10.1016/j...

We addressed this question using a modified SIR differential equations model coded in #rstats & deposited our code on @github https://abs.twimg.com/emoji/v2/... draggable="false" alt="👩🏼‍💻" title="Woman technologist (mittelheller Hautton)" aria-label="Emoji: Woman technologist (mittelheller Hautton)">https://abs.twimg.com/emoji/v2/... draggable="false" alt="🤓" title="Nerd-Gesicht" aria-label="Emoji: Nerd-Gesicht"> https://github.com/mwalte10/intra-urban_dengue_vaccination_impact">https://github.com/mwalte10/... 6/10

We found that models that ignore diffs between high-risk and low-risk areas underestimate #Dengvaxia’s impact *IF* it is targeted to those who could benefit from it the most 7/10

We also found that models that ignore diffs between high-risk and low-risk areas may overestimate #Dengvaxia’s impact for vaccinated people living in low-risk areas 8/10

This could put vaccinated people living in low-risk areas at greater risk of severe disease is serological screening is not highly specific https://abs.twimg.com/emoji/v2/... draggable="false" alt="😬" title="Grimasse schneidendes Gesicht" aria-label="Emoji: Grimasse schneidendes Gesicht"> 9/10