Jon B Cole, MD, Discover and Read the Best of Twitter Threads by @jonbcole2

Jon B Cole, MD

jonbcole2

Valproate metabolism:Most VPA is glucuronidated (50-80%).Most of the rest undergoes β-oxidation (up to 40%) in the mitochondria to 2-en-VPA-CoAA small amount (

Redox never been intuitive to me, so for the millionth time...REDUCTION is the GAIN of electrons by an atom. By gaining electrons (becoming more negatively charged) it is reduced.The electrons