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Eric Topol
EricTopol
What is the mortality rate for #COVID19 patients put on a mechanical ventilator? A new @JAMA_current https://jamanetwork.com/journals/jama/fullarticle/2765184@NorthwellHealth provided substantial data, adding to the UK registry, and 4 other published
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Adding to the above slide of no evidence, update today:@NIH panel recommends against Hydroxychloroquine (H) and Azithromycin (A)https://www.npr.org/sections/coronavirus-live-updates/2020/04/21/840341224/nih-panel-recommends-against-drug-combination-t
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The Asymptomatic #COVID19 Infection Rate.@danieloran, my colleague @ScrippsRTI, compiled all of the available data, links, text and details from 8 cohorts: https://www.scripps.edu/science-and-medicine/translational-institute/about/news/sarc-cov-2-inf
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To see that 20% of US #COVID19 infections are among the #healthcare workforce is sickening.Not only were 1000s of American deaths preventable, but not getting ahead of the outbreak AND
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The #COVID19 aerosol and droplets with speech, visualized. If #Masks4All hadn't sunk in by this late juncture, seeing is believing. Loud speech is worse. @NEJM today https://www.nejm.org/doi/full/10.1056/NEJMc2007800?query=featured_home Check out
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Lessons from Iceland, a model country for #COVID19 containment, from extensive population testing and virus sequencinghttps://www.nejm.org/doi/full/10.1056/NEJMoa2006100?query=featured_home @NEJM I want to add 2 notable points I learned from this rep
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Smartphone contact tracing is really clever, promising, fulfilling a major unmet need. The @apple @google collaboration is terrific, but the idea came earlier from @MIT and Singapore; it would have
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The route to reopen?Testing at scale is needed, but that's not enough.I wrote an oped on how we can use our digital infrastructure to guide us on the unchartered exit-ramp
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The antibody story to #COVID19 is not simple:1. Some people w/ infection don't develop much IgG (it's about level, not just 0|1)https://www.scmp.com/news/china/science/article/3078840/coronavirus-low-antibody-levels-raise-questions-about2. Pe
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Big for #COVID19 therapy: the compassionate use results for remdesivir in 53 patients looks very encouraging, especially in very sick patients on mechanical ventilation with 18% fatality (only, expect >
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There's been recent reports of the crystal structure of #COVID19. But now the crystal structure of the antibody, derived from a patient who recovered, w/ implications for vaccine devp't https://science.sciencemag.org/content/sci/early/2020/04
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April 7th outlook for #COVID19 fatality curves:1. The US flattening is easily seen now, but tops the chart and is headed towards 2,000/day2. New York shows the same story compared
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