#Thrombotic

Menaka Pai, MSc MD FRCPC

Okay one more thread before bed! Lots of Qs asking "what IS VITT?" Before I get to that, if you'd like an AWESOME metaphor about vaccine choice, please read my

Why am I now opposed to any further AstraZeneca vaccine being used in Canada? I want to walk you through the math we have available.First, I am using some risk-benefit

Menaka Pai, MSc MD FRCPC

LONG week on call @HamHealthSci. Lots of calls about #VITT post AZ vaccine. I'm transparent w my patients - I believe empowerment leads to earlier detection, better outcomes, less stress.

Jeremy Faust MD MS (ER physician)

Two highly concerning papers now live in the New England Journal of Medicine regarding the adenovirus-based AstraZeneca/Oxford vaccine.A small number of patients appear to have had serious clotting events with

Scott Gottlieb, MD

ScottGottliebMD

THREAD: There's a growing body of data to strongly suggest #COVID19 predisposes to both venous and arterial thromboembolism due to excessive inflammation, hypoxia, immobilization and diffuse intravascular coagulation. This may

Darren Markland

Everyone keeps telling you that the side effects from AstraZeneca and Jansen vaccines are rare and you should get the vaccine. I totally 100% agree with this, but trust is

Vincent Rajkumar

Astra Zeneca vaccine & blood clots. Summary.Rare form of blood clots plus low platelets. ~60% involve veins of brain. Almost all after 1st dose. Risk (UK MHRA): 1 in 250,000

DrSimonAshworth

How should we consider #COVID19?This is primarily a vitally induced thrombotic disease spread by droplets Post-mortems tell us the virus causes endothelial damage and overt blood clots in both small

Yes, the AstraZeneca vaccine-thrombosis association is causal.The temporal relationship is strong, it’s not seen with mRNA vaccines, and there’s a plausible mechanism analogous to heparin-induced thrombocytopenia (HIT)https://www.nejm.o

Plain English thread on how VITT might work, according to the latest Greinacher findings https://www.researchsquare.com/article/rs-440461/v1. One of your immune system's jobs is to deal with infections like colds and flus.

Rajeev Jayadevan

RajeevJayadevan

AstraZeneca Vaccine and clots: this important paper from Germany proves that VITT is not the result of cross-reactivity between anti-spike antibodies and platelet factor 4 (PF4). See thread and links

Chris von Csefalvay

chrisvcsefalvay

The trending wild-ass guess on #COVID19 of the day is this paper by gastroenterologist Farid Jalali, joining a spate of papers that boil down to explaining how respiratory symptoms in

Daniela Hermelin, MD

MaternalFetalMedicine #Blooducation conference. Topic: #TTP in pregnancy. We focused on thrombotic microangiopathic hemolytic anemias & shear wonder of the #schistocyte. Rock, Paper, Scissors, Shoot. Let's recap on the some of

Craig Spencer MD MPH

Craig_A_Spencer

Hi Kelly,Yes, this is something everyone taking care of #COVID19 patients has seen. We still don't exactly which patients will get these blood clots or why, but they're likely leading

Stage II of Virus and Bacteria Synergistic Infection of Covid-19: A physical model 0. Recap:Virus breaks cell and ECM adhesion, letting the endogenous bacteria in:https://twitter.com/joshux321/status/1264387117200756736?s=20The virus is lar

so today's webinar is from the ISTH on coagulopathy in #COVID19 A very elevated d-dimer is seen in non-survivors from chinese data#covid19 Like DIC but not quitea microangiopathy?#covid19 #COVID19 is