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How can 
genomic screening be implemented in diverse populations?
Our new study in @GenomeMedicine explores this in the ancestrally diverse BioMe Biobank @IcahnMountSinai in NYC 
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-021-00832-y
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genomic screening be implemented in diverse populations?Our new study in @GenomeMedicine explores this in the ancestrally diverse BioMe Biobank @IcahnMountSinai in NYC https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-021-00832-y
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We launched a pilot genomic screening program to return results for
Hereditary breast and ovarian cancer syndrome
Lynch syndrome
Familial hypercholesterolemia[
CDC Tier 1 conditions: https://www.cdc.gov/genomics/implementation/toolkit/tier1.htm]AND
Hereditary transthyretin amyloidosis (hATTR)2/6
![We launched a pilot genomic screening program to return results forHereditary breast and ovarian cancer syndromeLynch syndromeFamilial hypercholesterolemia[CDC Tier 1 conditions: https://www.cdc.gov/genomics/implementation/toolkit/tier1.htm]ANDHereditary transthyretin amyloidosis (hATTR)2/6](https://pbs.twimg.com/media/EttxYORWYAAU9HJ.jpg "We launched a pilot genomic screening program to return results forHereditary breast and ovarian cancer syndromeLynch syndromeFamilial hypercholesterolemia[CDC Tier 1 conditions: https://www.cdc.gov/genomics/implementation/toolkit/tier1.htm]ANDHereditary transthyretin amyloidosis (hATTR)2/6")
Why hATTR
hATTR is common in African American & Hispanic/Latinx individuals (due to TTR V142I) 
hATTR causes cardiomyopathy & heart failure
hATTR diagnosis is challenging & often delayed or missed 
new treatments improve outcomes when used early 
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hATTR is common in African American & Hispanic/Latinx individuals (due to TTR V142I) hATTR causes cardiomyopathy & heart failurehATTR diagnosis is challenging & often delayed or missed new treatments improve outcomes when used early 3/6
The addition of TTR expanded the reach of our genomic screening program to African American, Hispanic/Latinx, and Spanish-speaking individuals. [
See https://www.mdpi.com/2075-4426/11/1/49 for our study characterizing hATTR-related features in those who received TTR V142I results.]4/6
![The addition of TTR expanded the reach of our genomic screening program to African American, Hispanic/Latinx, and Spanish-speaking individuals. [See https://www.mdpi.com/2075-4426/11/1/49 for our study characterizing hATTR-related features in those who received TTR V142I results.]4/6](https://pbs.twimg.com/media/EttzYLWWQAI16mg.jpg "The addition of TTR expanded the reach of our genomic screening program to African American, Hispanic/Latinx, and Spanish-speaking individuals. [See https://www.mdpi.com/2075-4426/11/1/49 for our study characterizing hATTR-related features in those who received TTR V142I results.]4/6")
Also, most BioMe participants across race/ethnicity groups are interested in receiving genomic results! 
This is just the start of our mission to translate genomic information intopatient care for diverse populations
with @EimearEKenny @SinaiGenHealth5/6
Huge thanks to all co-authors, including the amazingteam who discloses genomic results and counsels participants: @EmilySoperGC
@SabrinaASuckiel
@GiovannaBragan7
And most of all to participants of the BioMe Biobank @BronfmanInst @IcahnMountSinai @MountSinaiNYC
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