Thread by @EricTopol, Now with ~1,000 children and adolescents with multi-inflammatory syndrome in children (MIS-C), [...]

Now with ~1,000 children and adolescents with multi-inflammatory syndrome in children (MIS-C), it can be considered a new disease. Today new @NEJM reports and an editorial on its status. I& #39;ve made a summary of some key points to start

Here is the USA report of 186 patients with locations of diagnoses, organ involvement and labs
https://www.nejm.org/doi/full/10.1056/NEJMoa2021680?query=featured_home">https://www.nejm.org/doi/full/...

The outstanding editorial, by Michael Levin
https://www.nejm.org/doi/full/10.1056/NEJMe2023158
a">https://www.nejm.org/doi/full/... report from New York State to follow later

The outstanding editorial, by Michael Levin https://www.nejm.org/doi/full/... report from New York State to follow later

Here is the New York State report today of 99 patients
https://www.nejm.org/doi/full/10.1056/NEJMoa2021756?query=featured_coronavirus
with">https://www.nejm.org/doi/full/... clusters of manifestations (the high % skin, GI, cardiac, neurologic, KD=Kawasaki& #39;s), therapy used, and associated diagnoses

Here is the New York State report today of 99 patients https://www.nejm.org/doi/full/... clusters of manifestations (the high % skin, GI, cardiac, neurologic, KD=Kawasaki& #39;s), therapy used, and associated diagnoses

So there& #39;s a paradox of the vast majority of children and adolescents that are spared from either susceptibility or adverse outcomes; yet a rare subgroup with MIS-C. A commentary in today& #39;s @TheLancetRheum explores the immunologic considerations
https://www.thelancet.com/action/showPdf?pii=S2665-9913%2820%2930212-5">https://www.thelancet.com/action/sh...

Today the MISC-C report from France and accompanying editorial @LancetChildAdol
https://www.thelancet.com/action/showPdf?pii=S2352-4642%2820%2930175-9
https://www.thelancet.com/action/sh... href=" https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(20)30207-8/fulltext
consistent">https://www.thelancet.com/journals/... with distinct phenotype, 2 week lag and other points in the US reports this week

Today the MISC-C report from France and accompanying editorial @LancetChildAdol https://www.thelancet.com/action/sh... href=

https://www.thelancet.com/journals/... with distinct phenotype, 2 week lag and other points in the US reports this week" title="Today the MISC-C report from France and accompanying editorial @LancetChildAdol https://www.thelancet.com/action/sh... href=" https://www.thelancet.com/journals/lanchi/article/PIIS2352-4642(20)30207-8/fulltextconsistent">https://www.thelancet.com/journals/... with distinct phenotype, 2 week lag and other points in the US reports this week">

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